Scientia Silvae Sinicae ›› 2006, Vol. 42 ›› Issue (9): 69-73.doi: 10.11707/j.1001-7488.20060913
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Zhang Cunli1,Zhu Wei1,Li Xiaoming1,Su Baofeng1,Yan Xiaoying2
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Abstract:
Steroid saponins ? was extracted from the rhizomes of Smilax scobinicaulis by systemic solvents. Different polarity steroid saponins R-5、R-6、R-7、R-8、R-9 and R-10 were isolated by DM-101 with different ethyl alcohol, four compounds were isolated from R-6 and R-8 separately by column chromatogramphy on silica gel,sephedax LH-20 and ODS. Sample R, R-5、R-6、R-7、R-8、R-9 and the isolated compounds was tested against six bacterium and five fungus respectively.The results indicated that sample R, R-5 and R-6 have weak or almost no inhibitory activity; But R-7、R-8、R-9 and the four compounds had remarkable inhibitory activity against almost all the tested bacterium and fungus. Four compounds were all steroid saponins determined as laxogenin-3-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside (Ⅰ);laxogenin-3-O-β-D-gluco-pyrnosyl -(1→4)-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside (Ⅱ);3β,27-dihydroxy-(25s)-5α-spiro-stan-6-one3-O-β-D- glucopyrnosyl-(1→4)-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside (Ⅲ) and (25D)spirost-5-en-3β,17α,27-triol-3-O-β-D-glucopyranosyl-(1→4)-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyran-oside (Ⅳ). Compound Ⅲ was first isolated from S. scobinicaulis. Steroid saponins from rhizomes of S. scobinicaulis have inhibitory activity and there are inhibitory activity active molecule cluster and their opposing molecule cluster.
Key words: Smilax scobinicaulis, steroid saponins, antisepsis, structure identify
Zhang Cunli;Zhu Wei;Li Xiaoming;Su Baofeng;Yan Xiaoying. Antisepsis Activity of the Rhizomes of Smilax scobinicaulis[J]. Scientia Silvae Sinicae, 2006, 42(9): 69-73.
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URL: http://www.linyekexue.net/EN/10.11707/j.1001-7488.20060913
http://www.linyekexue.net/EN/Y2006/V42/I9/69