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Scientia Silvae Sinicae ›› 2010, Vol. 46 ›› Issue (2): 162-165.doi: 10.11707/j.1001-7488.20100227

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Bacteriostasis and Chemical Components of the Neutral Lipophilic Components in Zanthoxylum dissitum

Ma Yingzi1,Wang Ping1,Yuan Yuan2,Wei Xiyuan2,Pei Gang2,He Guixia2   

  1. 1.School of Life Science and Technology, Central South University of Forestry and Technology Changsha 410004; 2.Hunan University of Chinese Medicine Changsha 410208
  • Received:2009-05-19 Revised:1900-01-01 Online:2010-02-25 Published:2010-02-25

Abstract:

Effects of bacteriostasis of the Neutral Lipophilic Components in Zanthoxylum dissitum were studied. The neutral lipophilic extract was fractionated through SiO2 column and the products were identified by 1H-NMR, 13C-NMR and MS. The results showed that the fraction exhibited strong bacteriostasis activity to Staphylococcus aureus and Salmonella sp. and also showed more or less inhibition on Escherichia coli. Six components were obtained, namely triacontane, 1-hexadecanol, β-sitosterol, ursolic acid, isopimpinellin and bergapten. Except for β-sitosterol, the others were isolated from the plant for the first time. After the preliminary analysis, the coumarins were considered as the active components of bacteriostasis activity.

Key words: Zanthoxylum dissitum, lipophilic property, bacteriostasis activity, chemical components, spectral analysis